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1

BOOK REVIEWS

Beran, Carol, Darnell, Regna, Heasley, Lynne, Hoff, Joan whitman, Holter, Desiree, Hurt, R. Douglas, Lamar, Celita, McHugh, James, Murphy, Thomas, Nord, Douglas, Parker, Richard, Simon, Sherry, Stuart

Journal:

The American Review of Canadian Studies

Year:

2008

Language:

english

File:

PDF, 1.83 MB

english, 2008

2

Evaluation of FGFR3 as a Therapeutic Target in Head and Neck Squamous Cell Carcinoma

von Mässenhausen, Anne, Deng, Mario, Billig, Hannah, Queisser, Angela, Vogel, Wenzel, Kristiansen, Glen, Schröck, Andreas, Bootz, Friedrich, Göke, Friederike, Franzen, Alina, Heasley, Lynn, Kirfel, Ju

Journal:

Targeted Oncology

Year:

2016

Language:

english

File:

PDF, 903 KB

english, 2016

3

Translating mesothelioma molecular genomics and dependencies into precision oncology-based therapies

Hinz, Trista K., Heasley, Lynn E.

Journal:

Seminars in Cancer Biology

Year:

2019

Language:

english

File:

PDF, 1.34 MB

english, 2019

4

Akt negatively regulates the cJun N-terminal kinase pathway in PC12 cells

Valerie Levresse, Laura Butterfield, Eve Zentrich, Lynn E. Heasley

Journal:

Journal of Neuroscience Research

Year:

2000

Language:

english

File:

PDF, 196 KB

english, 2000

5

Tyrosine kinase growth factor receptors but not seven-membrane–spanning receptors or phorbol esters activate mitogen-activated protein kinase in rat hepatocytes

Dr Pere Ginès, Xiaomei Li, Jeffrey L. Zamarripa, Susan E. S. Brown, Eric D. Wieder, Toshikazu Nakamura, Phillip S. Guzelian, Robert W. Schrier, Lynn E. Heasley, Raphael A. Nemenoff

Journal:

Year:

1995

Language:

english

File:

PDF, 1012 KB

english, 1995

6

Activating mutations in the NH2- and COOH-terminal moieties of the Gsα subunit have dominant phenotypes and distinguishable kinetics of adenylyl cyclase stimulation

Sunil K. Gupta, N. Dhanasekaran, Lynn E. Heasley, Gary L. Johnson

Journal:

Journal of Cellular Biochemistry

Year:

1991

Language:

english

File:

PDF, 834 KB

english, 1991

7

Multiple signaling conduits regulate global differentiation-specific gene expression in PC12 cells

Lindsay Marek, Valerie Levresse, Claudia Amura, Eve Zentrich, Vicki Van Putten, Raphael A. Nemenoff, Lynn E. Heasley

Journal:

Journal of Cellular Physiology

Year:

2004

Language:

english

File:

PDF, 216 KB

english, 2004

8

Signalling in stem cells

Heasley, Lynn E., Petersen, Bryon E.

Journal:

Year:

2004

Language:

english

File:

PDF, 137 KB

english, 2004

9

Autocrine and paracrine signaling through neuropeptide receptors in human cancer

Heasley, Lynn E

Journal:

Year:

2001

Language:

english

File:

PDF, 166 KB

english, 2001

10

γ-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth

Winn, Robert A, Bremnes, Roy M, Bemis, Lynne, Franklin, Wilbur A, Miller, York E, Cool, Carlyne, Heasley, Lynn E

Journal:

Year:

2002

Language:

english

File:

PDF, 409 KB

english, 2002

11

Concise Review: Regulation of Embryonic Stem Cell Lineage Commitment by Mitogen-Activated Protein Kinases

Bernard Binétruy, Lynn Heasley, Frédéric Bost, Leslie Caron, Myriam Aouadi

Journal:

Year:

2007

Language:

english

File:

PDF, 259 KB

english, 2007

12

The fibroblast growth factor receptor signaling pathway as a mediator of intrinsic resistance to EGFR-specific tyrosine kinase inhibitors in non-small cell lung cancer

Scott A. Kono, Marianne E. Marshall, Kathryn E. Ware, Lynn E. Heasley

Journal:

Drug Resistance Updates

Year:

2009

Language:

english

File:

PDF, 523 KB

english, 2009

13

TRH regulates Kv1.5 gene expression through a Gαq-mediated PLC-independent pathway

Ting-Ting Zhang, Robert Gealy, Xinghua Lu, Lynn E Heasley, Koichi Takimoto, Edwin S Levitan

Journal:

Molecular and Cellular Endocrinology

Year:

2000

Language:

english

File:

PDF, 225 KB

english, 2000

14

Reactions of terminal alkynes with iodine in methanol

Heasley, Victor L., Shellhamer, Dale F., Heasley, Lynn E., Yaeger, David B., Heasley, Gene E.

Journal:

Journal of Organic Chemistry

Year:

1980

Language:

english

File:

PDF, 523 KB

english, 1980

15

Interferon-β-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through up-regulation of CD95 in CH31 B lymphoma cells

Eiko Takada, Kuniaki Shimo, Kikumi Hata, Maira Abiake, Yasuo Mukai, Masami Moriyama, Lynn Heasley, Junichiro Mizuguchi

Journal:

Experimental Cell Research

Year:

2005

Language:

english

File:

PDF, 746 KB

english, 2005

16

Bacteriophage ϵ15 is released intact from the surface of its host cell, Salmonella anatum, at acidic pH

Michael R. McConnell, Douglas D. McAbee, Lynn E. Heasley, James E. Schoelz, Darla Reel Harlow, Dan R. Starn

Journal:

Year:

1982

Language:

english

File:

PDF, 305 KB

english, 1982

17

Prostacyclin Inhibits Non-Small Cell Lung Cancer Growth by a Frizzled 9-Dependent Pathway That Is Blocked by Secreted Frizzled-Related Protein 1

Tennis, Meredith A., Van Scoyk, Michelle, Heasley, Lynn E., Vandervest, Katherine, Weiser-Evans, Mary, Freeman, Scott, Keith, Robert L., Simpson, Pete, Nemenoff, Raphael A., Winn, Robert A.

Journal:

Year:

2010

Language:

english

File:

PDF, 680 KB

english, 2010

18

[untitled]

Review by: Lynne Heasley

Journal:

Environmental History

Year:

1998

Language:

english

File:

PDF, 139 KB

english, 1998

19

Special Issue on Canada || Recentering North American Environmental History: Pedagogy and Scholarship in the Great Lakes Region

James Feldman and Lynne Heasley

Journal:

Environmental History

Year:

2007

Language:

english

File:

PDF, 766 KB

english, 2007

20

[untitled]

Review by: Lynne Heasley

Journal:

Environmental History

Year:

2006

Language:

english

File:

PDF, 110 KB

english, 2006

21

On Walking Contested Land: Doing Environmental History in West Africa and the United States

Journal:

Environmental History

Year:

2005

Language:

english

File:

PDF, 909 KB

english, 2005

22

Shifting Boundaries on a Wisconsin Landscape: Can GIS Help Historians Tell a Complicated Story?

Journal:

Year:

2003

Language:

english

File:

PDF, 4.48 MB

english, 2003

23

G Protein-Coupled Receptor Systems Involved in Cell Growth and Oncogenesis

DHANASEKARAN, N., HEASLEY, LYNN E., JOHNSON, GARY L.

Journal:

Endocrine Reviews

Year:

1995

Language:

english

File:

PDF, 1.81 MB

english, 1995

24

Mutation of glycine 49 to valine in the .alpha. subunit of Gs results in the constitutive elevation of cyclic AMP synthesis

Woon, Chee Wai, Heasley, Lynn, Osawa, Shoji, Johnson, Gary L.

Journal:

Year:

1989

Language:

english

File:

PDF, 1.75 MB

english, 1989

25

The politics of manure: Resource tenure and the agropastoral economy in southwestern Niger

Heasley, Lynne, Delehanty, James

Journal:

Society & Natural Resources

Year:

1996

Language:

english

File:

PDF, 1.21 MB

english, 1996

26

Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data

Ryall, Karen A., Shin, Jimin, Yoo, Minjae, Hinz, Trista K., Kim, Jihye, Kang, Jaewoo, Heasley, Lynn E., Tan, Aik Choon

Journal:

Year:

2015

Language:

english

File:

PDF, 782 KB

english, 2015

27

Prolactin Stimulates Activation of c- jun N-Terminal Kinase (JNK)

Schwertfeger, Kathryn L., Hunter, Seija, Heasley, Lynn E., Levresse, Valerie, Leon, Ronald P., DeGregori, James, Anderson, Steven M.

Journal:

Molecular Endocrinology

Year:

2000

Language:

english

File:

PDF, 255 KB

english, 2000

28

Mitogen-Activated Protein Kinase Activation Resulting from Selective Oncogene Expression in NIH 3T3 and Rat 1a Cells

Carme Gallego, Sunil K. Gupta, Lynn E. Heasley, Nan-Xin Qian and Gary L. Johnson

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.25 MB

english, 1992

29

Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung Cancer

Zhang, Liping, Yu, Hui, Badzio, Andrzej, Boyle, Theresa A., Schildhaus, Hans-Ulrich, Lu, Xian, Dziadziuszko, Rafal, Jassem, Jacek, Varella-Garcia, Marileila, Heasley, Lynn E., Kowalewski, Ashley A., E

Journal:

Journal of Thoracic Oncology

Year:

2015

Language:

english

File:

PDF, 1.68 MB

english, 2015

30

γ-Catenin Expression Is Reduced or Absent in a Subset of Human Non-small Cell Lung Cancers, and Its Re-expression Inhibits Cell Growth

Winn, Robert A., Heasley, Lynn E.

Journal:

Year:

2004

Language:

english

File:

PDF, 83 KB

english, 2004

31

Stress- and cell type-dependent regulation of transfected c-Jun N-terminal kinase and mitogen-activated protein kinase kinase isoforms

BUTTERFIELD, Laura, ZENTRICH, Eve, BEEKMAN, Andrew, HEASLEY, Lynn E.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

32

Suppression of smooth-muscle α-actin expression by platelet-derived growth factor in vascular smooth-muscle cells involves Ras and cytosolic phospholipase A2

LI, Xiaomei, PUTTEN, Vicki VAN, ZARINETCHI, Fariba, NICKS, E. Michael, THALER, Seth, HEASLEY, E. Lynn, NEMENOFF, A. Raphael

Journal:

Biochemical Journal

Year:

1997

Language:

english

File:

PDF, 381 KB

english, 1997

33

Stress- and cell type-dependent regulation of transfected c-Jun N-terminal kinase and mitogen-activated protein kinase kinase isoforms

BUTTERFIELD, Laura, ZENTRICH, Eve, BEEKMAN, Andrew, HEASLEY, Lynn E.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

34

P3.02b-084 Rational Combinations to Improve Outcome for EGFR-TKIs in NSCLCs with EGFR Mutations

Helfrich, Barbara, Scarborough, Hannah, Heasley, Lynn, Ryall, Karen, Tan, Aik-Choon, Degregori, James, Bunn, Paul

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 125 KB

english, 2017

35

MA15.11 Acquired Resistance Mechanisms to EGFR Kinase Inhibitors Alter PD-L1 Expression Status in Lung Cancer

Suda, Kenichi, Rozeboom, Leslie, Rivard, Christopher, Yu, Hui, Melnick, Mary Ann, Hinz, Trista, Ellison, Kim, Chan, Daniel, Politi, Katerina, Heasley, Lynn, Mitsudomi, Tetsuya, Hirsch, Fred R.

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 778 KB

english, 2017

36

Therapy-induced E-cadherin downregulation alters expression of programmed death ligand-1 in lung cancer cells

Suda, Kenichi, Rozeboom, Leslie, Rivard, Christopher J., Yu, Hui, Ellison, Kim, Melnick, Mary Ann C., Hinz, Trista K., Chan, Daniel, Heasley, Lynn E., Politi, Katerina, Mitsudomi, Tetsuya, Hirsch, Fre

Journal:

Year:

2017

Language:

english

File:

PDF, 1.62 MB

english, 2017

37

New Therapeutic Strategies for Lung Cancer

Bunn, Paul A., Soriano, Ariel, Johnson, Gary, Heasley, Lynn

Journal:

Year:

2000

Language:

english

File:

PDF, 195 KB

english, 2000

38

The Tumor Microenvironment Regulates Sensitivity of Murine Lung Tumors to PD-1/PDL1 Antibody Blockade

Li, Howard Y, McSharry, Maria V, Bullock, Bonnie, Nguyen, Teresa T, Kwak, Jeff, Poczobutt, Joanna M, Sippel, Trisha R., Heasley, Lynn E., Weiser-Evans, Mary C., Clambey, Eric T, Nemenoff, Raphael A.

Journal:

Cancer Immunology Research

Year:

2017

Language:

english

File:

PDF, 8.27 MB

english, 2017

39

Ionizing radiation sensitizes tumors to PD-L1 immune checkpoint blockade in orthotopic murine head and neck squamous cell carcinoma

Oweida, Ayman, Lennon, Shelby, Calame, Dylan, Korpela, Sean, Bhatia, Shilpa, Sharma, Jaspreet, Graham, Caleb, Binder, David, Serkova, Natalie, Raben, David, Heasley, Lynn, Clambey, Eric, Nemenoff, Rap

Journal:

Year:

2017

Language:

english

File:

PDF, 3.28 MB

english, 2017

40

Mechanisms of rapid cancer cell reprogramming initiated by targeted receptor tyrosine kinase inhibitors and inherent therapeutic vulnerabilities

Kleczko, Emily K., Heasley, Lynn E.

Journal:

Molecular Cancer

Year:

2018

Language:

english

File:

PDF, 670 KB

english, 2018

41

Inhibition of EphB4-ephrin-B2 signaling enhances response to Cetuximab-radiation therapy in head and neck cancers

Bhatia, Shilpa, Sharma, Jaspreet, Bukkapatnam, Sanjana, Oweida, Ayman, Lennon, Shelby, Phan, Andy V, Milner, Dallin, Uyanga, Nomin, Jimeno, Antonio, Raben, David, Somerset, Hilary, Heasley, Lynn, Kara

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 8.97 MB

english, 2018

42

Resistance to ROS1 Inhibition Mediated by EGFR Pathway Activation in Non-Small Cell Lung Cancer

Davies, Kurtis D., Mahale, Sakshi, Astling, David P., Aisner, Dara L., Le, Anh T., Hinz, Trista K., Vaishnavi, Aria, Bunn, Paul A., Heasley, Lynn E., Tan, Aik-Choon, Camidge, D. Ross, Varella-Garcia,

Journal:

Year:

2013

Language:

english

File:

PDF, 4.21 MB

english, 2013

43

Rapidly Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in NSCLC Cell Lines through De-Repression of FGFR2 and FGFR3 Expression

Ware, Kathryn E., Marshall, Marianne E., Heasley, Lydia R., Marek, Lindsay, Hinz, Trista K., Hercule, Paula, Helfrich, Barbara A., Doebele, Robert C., Heasley, Lynn E., Bernhard, Eric J.

Journal:

Year:

2010

Language:

english

File:

PDF, 533 KB

english, 2010

44

Heterotrimeric G-Protein, Gα16, Is a Critical Downstream Effector of Non-Canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer

Avasarala, Sreedevi, Bikkavilli, Rama Kamesh, Van Scoyk, Michelle, Zhang, Wei, Lapite, Ajibike, Hostetter, Logan, Byers, Joshua T., Heasley, Lynn E., Sohn, Jang Won, Winn, Robert A., Deb, Sumitra

Journal:

Year:

2013

Language:

english

File:

PDF, 2.39 MB

english, 2013

45

An Inducible TGF-β2-TGFβR Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases

Kleczko, Emily K., Kim, Jihye, Keysar, Stephen B., Heasley, Lydia R., Eagles, Justin R., Simon, Matthew, Marshall, Marianne E., Singleton, Katherine R., Jimeno, Antonio, Tan, Aik-Choon, Heasley, Lynn

Journal:

Year:

2015

Language:

english

File:

PDF, 880 KB

english, 2015

46

Burning waters: with the Great Lakes, this is no time for patience

Journal:

Year:

2018

Language:

english

File:

PDF, 86 KB

english, 2018

47

Preselection of lung cancer cases using FGFR1 mRNA and gene copy number for treatment with ponatinib.

Ng, Terry L., Yu, Hui, Smith, Derek E., Boyle, Theresa A., York, Emily R., Leedy, Scott, Gao, Dexiang, Aisner, Dara L., Van Bokhoven, Adrie, Heasley, Lynn E., Hirsch, Fred R., Camidge, D. Ross

Journal:

Clinical Lung Cancer

Year:

2018

Language:

english

File:

PDF, 1.06 MB

english, 2018

48

Subcellular Localization and Activity of the Mitogen-Activated Protein Kinase Kinase 7 (MKK7) γ Isoform are Regulated through Binding to the Phosphatase Calcineurin

Gibson, Emily S., Woolfrey, Kevin M., Li, Huiming, Hogan, Patrick G., Nemenoff, Raphael A., Heasley, Lynn E., Dell’Acqua, Mark L.

Journal:

Molecular Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.99 MB

english, 2019

49

ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer

Pilling, Amanda B., Kim, Jihye, Estrada-Bernal, Adriana, Zhou, Qiong, Le, Anh T., Singleton, Katherine R., Heasley, Lynn E., Tan, Aik Choon, DeGregori, James, Doebele, Robert C.

Journal:

Year:

2018

Language:

english

File:

PDF, 4.83 MB

english, 2018

50

Therapeutic opportunity in innate immune response induction by oncogene-targeted drugs

Sisler, Daniel J, Heasley, Lynn E

Journal:

Future Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 179 KB

english, 2019